GNAO1

GNAO1

Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, also known as GNAO1, is a human gene.cite web | title = Entrez Gene: GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2775| accessdate = ]

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References

Further reading

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*cite journal | author=Raymond JR, Mukhin YV, Gelasco A, "et al." |title=Multiplicity of mechanisms of serotonin receptor signal transduction. |journal=Pharmacol. Ther. |volume=92 |issue= 2-3 |pages= 179–212 |year= 2002 |pmid= 11916537 |doi=
*cite journal | author=Coupry I, Duzic E, Lanier SM |title=Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. II. Preferential coupling of the alpha 2C-adrenergic receptor to the guanine nucleotide-binding protein, Go. |journal=J. Biol. Chem. |volume=267 |issue= 14 |pages= 9852–7 |year= 1992 |pmid= 1349607 |doi=
*cite journal | author=Denker BM, Neer EJ, Schmidt CJ |title=Mutagenesis of the amino terminus of the alpha subunit of the G protein Go. In vitro characterization of alpha o beta gamma interactions. |journal=J. Biol. Chem. |volume=267 |issue= 9 |pages= 6272–7 |year= 1992 |pmid= 1556134 |doi=
*cite journal | author=Murtagh JJ, Eddy R, Shows TB, "et al." |title=Different forms of Go alpha mRNA arise by alternative splicing of transcripts from a single gene on human chromosome 16. |journal=Mol. Cell. Biol. |volume=11 |issue= 2 |pages= 1146–55 |year= 1991 |pmid= 1899283 |doi=
*cite journal | author=Yi F, Denker BM, Neer EJ |title=Structural and functional studies of cross-linked Go protein subunits. |journal=J. Biol. Chem. |volume=266 |issue= 6 |pages= 3900–6 |year= 1991 |pmid= 1899868 |doi=
*cite journal | author=Tsukamoto T, Toyama R, Itoh H, "et al." |title=Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two different mRNAs are generated by alternative splicing. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 8 |pages= 2974–8 |year= 1991 |pmid= 1901650 |doi=
*cite journal | author=Gabrion J, Brabet P, Nguyen Than Dao B, "et al." |title=Ultrastructural localization of the GTP-binding protein Go in neurons. |journal=Cell. Signal. |volume=1 |issue= 1 |pages= 107–23 |year= 1990 |pmid= 2518353 |doi=
*cite journal | author=Lavu S, Clark J, Swarup R, "et al." |title=Molecular cloning and DNA sequence analysis of the human guanine nucleotide-binding protein Go alpha. |journal=Biochem. Biophys. Res. Commun. |volume=150 |issue= 2 |pages= 811–5 |year= 1988 |pmid= 3124840 |doi=
*cite journal | author=Zumbihl R, Breuiller-Fouché M, Carrette J, "et al." |title=Up-regulation in late pregnancy of both Go1 alpha and Go2 alpha isoforms in human myometrium. |journal=Eur. J. Pharmacol. |volume=288 |issue= 1 |pages= 9–15 |year= 1995 |pmid= 7705473 |doi=
*cite journal | author=Grassie MA, Milligan G |title=Analysis of the relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these polypeptides in rat 1 fibroblasts. |journal=Biochem. J. |volume=306 ( Pt 2) |issue= |pages= 525–30 |year= 1995 |pmid= 7887906 |doi=
*cite journal | author=Wu HC, Lin CT |title=Association of heterotrimeric GTP binding regulatory protein (Go) with mitosis. |journal=Lab. Invest. |volume=71 |issue= 2 |pages= 175–81 |year= 1994 |pmid= 8078296 |doi=
*cite journal | author=Nitta K, Uchida K, Kawashima A, "et al." |title=Identification of GTP-binding proteins in human glomeruli. |journal=Nippon Jinzo Gakkai shi |volume=36 |issue= 1 |pages= 9–12 |year= 1994 |pmid= 8107314 |doi=
*cite journal | author=Georgoussi Z, Carr C, Milligan G |title=Direct measurements of in situ interactions of rat brain opioid receptors with the guanine nucleotide-binding protein Go. |journal=Mol. Pharmacol. |volume=44 |issue= 1 |pages= 62–9 |year= 1993 |pmid= 8393523 |doi=
*cite journal | author=Laugwitz KL, Allgeier A, Offermanns S, "et al." |title=The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 1 |pages= 116–20 |year= 1996 |pmid= 8552586 |doi=
*cite journal | author=Kawano N, Ito T, Kitamura H, "et al." |title=Immunoexpression of the alpha subunit of a guanine nucleotide-binding protein (Go) in pulmonary neuroendocrine cells and neoplasms. |journal=Pathol. Int. |volume=46 |issue= 6 |pages= 393–8 |year= 1997 |pmid= 8869990 |doi=
*cite journal | author=De Vries L, Elenko E, Hubler L, "et al." |title=GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 26 |pages= 15203–8 |year= 1997 |pmid= 8986788 |doi=
*cite journal | author=Valenzuela D, Han X, Mende U, "et al." |title=G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 5 |pages= 1727–32 |year= 1997 |pmid= 9050846 |doi=
*cite journal | author=Chen C, Zheng B, Han J, Lin SC |title=Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast. |journal=J. Biol. Chem. |volume=272 |issue= 13 |pages= 8679–85 |year= 1997 |pmid= 9079700 |doi=
*cite journal | author=Natochin M, Lipkin VM, Artemyev NO |title=Interaction of human retinal RGS with G-protein alpha-subunits. |journal=FEBS Lett. |volume=411 |issue= 2-3 |pages= 179–82 |year= 1997 |pmid= 9271201 |doi=
*cite journal | author=Busconi L, Denker BM |title=Analysis of the N-terminal binding domain of Go alpha. |journal=Biochem. J. |volume=328 ( Pt 1) |issue= |pages= 23–31 |year= 1998 |pmid= 9359829 |doi=

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  • Heterotrimeric G protein — [ http://www.pdb.org/pdb/static.do?p=education discussion/molecule of the month/pdb58 1.html more details...] )] G protein usually refers to the membrane associated heterotrimeric G proteins, sometimes referred to as the large G proteins . These… …   Wikipedia

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