- Wilhelm Olivier Leube
Wilhelm Olivier Leube (
September 14 ,1842 - 1922) was a Germaninternist who was a native ofUlm . He studied medicine inTübingen ,Zurich ,Berlin andMunich , and in 1868 became an assistant at the medical clinic inErlangen . In 1872 he became a professor ofpathology and specialtherapy , as well as director of the medical clinic inJena . Afterwards he was a professor at Erlangen (1874-1885) andWürzburg . At Jena, one of his assistants was noted physicianOttomar Rosenbach (1851-1907).Wilhelm Leube is remembered for his work with
gastric andintestinal disorders, and his pioneer research of "nervousdyspepsia ". He believed that gastric irritation was often caused by the effects of food on the sensory nerves of thestomach , and performed extensive studies ondigestion . In 1871 he introduced a procedure known asintubation in order to retrieve contents of the stomach for analysis. Later he introduced "test meals" of different types of food, which would be served to patients, and afterwards retrieved via Leube's "gastric tube" at scheduled times. Through these procedures, Leube researched the degree of digestion of the test meal, as well as the quantity and concentration of acid andpepsin in the patients' stomach.Among Leube's written works was an influential 1875 treatise of gastro-enterological diseases called "Die Krankheiten des Magens und Darms", which was included in
Hugo Wilhelm von Ziemssen 's "Handbuch der spediellen Pathologie und Therapie".References
* [http://www.clinchem.org/cgi/content/full/43/5/837 Gastric tubes, meals, acid, and analysis]
* [http://translate.google.com/translate?hl=en&sl=de&u=http://www.knerger.de/Die_Personen/wissensch__28/wissensch__29/wissenschaftler_30/wissenschaftler_31/wissenschaftler_32/wissenschaftler_33/hauptteil_wissenschaftler_33.html&sa=X&oi=translate&resnum=4&ct=result&prev=/search%3Fq%3DLeube%2BUlm%2BErlangen%26hl%3Den%26sa%3DG Wissenschaftler XXXIII- Scientific Biographies (Google-translated from German)]
* [http://ndt.oxfordjournals.org/cgi/content/full/18/7/1281 The history of proteinuria before Richard Bright]
Wikimedia Foundation. 2010.