Lipopolysaccharide 3-alpha-galactosyltransferase

In enzymology, a lipopolysaccharide 3-alpha-galactosyltransferase (EC number|2.4.1.44) is an enzyme that catalyzes the chemical reaction

:UDP-galactose + lipopolysaccharide $ightleftharpoons$ UDP + 3-alpha-D-galactosyl- [lipopolysaccharide glucose]

Thus, the two substrates of this enzyme are UDP-galactose and lipopolysaccharide, whereas its two products are UDP and [3-alpha-D-galactosyl- [lipopolysaccharide glucose] .

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase. Other names in common use include UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase, UDP-galactose:polysaccharide galactosyltransferase, uridine diphosphate galactose:lipopolysaccharide, alpha-3-galactosyltransferase, uridine diphosphogalactose-lipopolysaccharide, and alpha,3-galactosyltransferase. This enzyme participates in lipopolysaccharide biosynthesis and glycan structures - biosynthesis 2.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1GA8 and PDB link|1SS9.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9073-98-7."

Gene Ontology (GO) codes