- Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase
In
enzymology , an alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (EC number|2.4.99.3) is anenzyme that catalyzes thechemical reaction :CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein ightleftharpoons CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)- glycoprotein
Thus, the two substrates of this enzyme are
CMP-N-acetylneuraminate andglycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein , whereas its 3 products are CMP,glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)- , andglycoprotein .This enzyme belongs to the family of
transferase s, specifically thoseglycosyltransferase s that do not transfer hexosyl or pentosyl groups. The systematic name of this enzyme class is CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl )-glycoprotein alpha-2,6-N-acetylneuraminyltransferase. This enzyme participates ino-glycan biosynthesis andglycan structures - biosynthesis 1 .References
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External links
::"The
CAS registry number for this enzyme class is CAS registry|71124-50-0."Gene Ontology (GO) codes
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