Thiocyanate hydrolase

Thiocyanate hydrolase

In enzymology, a thiocyanate hydrolase (EC number|3.5.5.8) is an enzyme that catalyzes the chemical reaction

:thiocyanate + 2 H2O ightleftharpoons carbonyl sulfide + NH3 + HO-

Thus, the two substrates of this enzyme are thiocyanate and H2O, whereas its 3 products are carbonyl sulfide, NH3, and HO-.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. The systematic name of this enzyme class is thiocyanate aminohydrolase.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2DD4, PDB link|2DD5, PDB link|2DXB, and PDB link|2DXC.

References

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External links

Gene Ontology (GO) codes


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