Beta-ureidopropionase

Beta-ureidopropionase

In enzymology, a beta-ureidopropionase (EC number|3.5.1.6) is an enzyme that catalyzes the chemical reaction

:N-carbamoyl-beta-alanine + H2O ightleftharpoons beta-alanine + CO2 + NH3

Thus, the two substrates of this enzyme are N-carbamoyl-beta-alanine and H2O, whereas its 3 products are beta-alanine, CO2, and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-carbamoyl-beta-alanine amidohydrolase. This enzyme participates in 3 metabolic pathways: pyrimidine metabolism, beta-alanine metabolism, and pantothenate and coa biosynthesis.

tructural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1R3N, PDB link|1R43, PDB link|2V8D, PDB link|2V8G, PDB link|2V8H, and PDB link|2V8V.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9027-27-4."

Gene Ontology (GO) codes


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