3-hydroxyisobutyryl-CoA hydrolase
- 3-hydroxyisobutyryl-CoA hydrolase
In enzymology, a 3-hydroxyisobutyryl-CoA hydrolase (EC number|3.1.2.4) is an enzyme that catalyzes the chemical reaction
:3-hydroxy-2-methylpropanoyl-CoA + H2O CoA + 3-hydroxy-2-methylpropanoate
Thus, the two substrates of this enzyme are 3-hydroxy-2-methylpropanoyl-CoA and H2O, whereas its two products are CoA and 3-hydroxy-2-methylpropanoate.
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is 3-hydroxy-2-methylpropanoyl-CoA hydrolase. Other names in common use include 3-hydroxy-isobutyryl CoA hydrolase, and HIB CoA deacylase. This enzyme participates in 3 metabolic pathways: valine, leucine and isoleucine degradation, beta-alanine metabolism, and propanoate metabolism.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|9025-88-1."
Gene Ontology (GO) codes
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