Mitochondrial protein-transporting ATPase

mitochondrial protein-transporting ATPase
Identifiers
EC number	3.6.3.51
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a mitochondrial protein-transporting ATPase (EC 3.6.3.51) is an enzyme that catalyzes the chemical reaction

ATP + H₂O $\rightleftharpoons$ ADP + phosphate

Thus, the two substrates of this enzyme are ATP and H₂O, whereas its two products are ADP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (mitochondrial protein-importing).

References

• Rassow J; Meijer, M; Maarse, AC; Hönlinger, A; Dekker, PJ; Pfanner, N; Rassow, J (1997). "Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane". EMBO J. 16 (9): 2205–16. doi:10.1093/emboj/16.9.2205. PMC 1169823. PMID 9171336. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1169823. 
• Brunner M; Bauer, MF; Schneider, HC; Klaus, C; Dietmeier, K; Neupert, W; Brunner, M (1995). "The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system". Cell. 81 (7): 1085–93. doi:10.1016/S0092-8674(05)80013-3. PMID 7600576. 
• Voos W, Martin H, Krimmer T, Pfanner N (1999). "Mechanisms of protein translocation into mitochondria". Biochim. Biophys. Acta. 1422 (3): 235–54. PMID 10548718. 

This hydrolase article is a stub. You can help Wikipedia by expanding it.v · Categories: EC 3.6.3 Enzymes of unknown structure Hydrolase stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно сделать НИР? Voronezhsky Mature teratoma Look at other dictionaries: ATPase — ATPases are a class of enzymes that catalyze the decomposition of adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and a free phosphate ion. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses… …   Wikipedia P-type ATPase — Calcium ATPase, E2 Pi state Identifiers Symbol E1 E2 ATPase Pfam …   Wikipedia List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia Na+/K+-ATPase — Flow of ions. Alpha and beta units …   Wikipedia Membrane transport protein — A membrane transport protein (or simply transporter) is a membrane protein[1] involved in the movement of ions, small molecules, or macromolecules, such as another protein across a biological membrane. Transport proteins are integral membrane… …   Wikipedia ATP7A — ATPase, Cu++ transporting, alpha polypeptide PDB rendering based on 1aw0 …   Wikipedia Oxidative phosphorylation — The electron transport chain in the mitochondrion is the site of oxidative phosphorylation in eukaryotes. The NADH and succinate generated in the citric acid cycle are oxidized, releasing energy to power the ATP synthase. Oxidative… …   Wikipedia Copper in health — Normal absorption and distribution of copper. Cu = copper, CP = ceruloplasmin, green = ATP7B carrying copper. Copper is an essential trace element that is vital to the health of all living things (humans, plants, animals, and microorganisms). In… …   Wikipedia Wilson's disease — Classification and external resources A Kayser Fleischer ring (the brown ring on the edge of the iris) is common in Wilson s disease, especially when neurological symptoms are present ICD …   Wikipedia Disease — Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the… …   Medical dictionary 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”