Annamycin

Drugbox
IUPAC_name = (7"S",9"S")-7- [(2"R",3"R",4"R",5"R",6"S")-4,5-dihydroxy-3-iodo- 6-methyloxan-2-yl] oxy-6,9,11-trihydroxy-9- (2-hydroxyacetyl)-8,10-dihydro-7"H"-tetracene-5,12-dione

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CAS_number = 92689-49-1
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PubChem = 115212
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C=26 |H=25 |I=1 |O=11
molecular_weight = 640.375 g/mol
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Annamycin is an anthracycline antibiotic being investigated for the treatment of cancer.

Further reading

*cite journal |author=Priebe W |title=Mechanism of action-governed design of anthracycline antibiotics: a "turn-off/turn-on" approach |journal=Current Pharmaceutical Design |volume=1 |issue=1 |pages=51–68 |year=1995 |url=http://books.google.com/books?id=qq8uPl5YYuoC&pg=PA64&dq=annamycin&sig=ACfU3U16xCOaovfpgAQBeN9OolEo_mCiwQ#PPA51,M1
*cite journal |author=Trevino AV, Woynarowska BA, Herman TS, Priebe W, Woynarowski JM |title=Enhanced topoisomerase II targeting by annamycin and related 4-demethoxy anthracycline analogues |journal=Mol Cancer Ther |volume=3 |issue=11 |pages=1403–10 |year=2004 |month=November |pmid=15542779 |doi= |url=http://mct.aacrjournals.org/cgi/pmidlookup?view=long&pmid=15542779

External links

* [http://www.cancer.gov/Templates/db_alpha.aspx?CdrID=45025 National Cancer Institute Definition of Annamycin]