Pectate lyase

In enzymology, a pectate lyase (EC number|4.2.2.2) is an enzyme that catalyzes the chemical reaction

:Eliminative cleavage of (1->4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is (1->4)-alpha-D-galacturonan lyase. Other names in common use include polygalacturonic transeliminase, pectic acid transeliminase, polygalacturonate lyase, endopectin methyltranseliminase, pectate transeliminase, endogalacturonate transeliminase, pectic acid lyase, pectic lyase, alpha-1,4-D-endopolygalacturonic acid lyase, PGA lyase, PPase-N, endo-alpha-1,4-polygalacturonic acid lyase, polygalacturonic acid lyase, pectin trans-eliminase, and Polygalacturonic acid trans-eliminase. This enzyme participates in pentose and glucuronate interconversions.

tructural studies

As of late 2007, 32 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1AIR, PDB link|1BN8, PDB link|1EE6, PDB link|1GXM, PDB link|1GXN, PDB link|1GXO, PDB link|1JRG, PDB link|1JTA, PDB link|1O88, PDB link|1O8D, PDB link|1O8E, PDB link|1O8F, PDB link|1O8G, PDB link|1O8H, PDB link|1O8I, PDB link|1O8J, PDB link|1O8K, PDB link|1O8L, PDB link|1O8M, PDB link|1OOC, PDB link|1PCL, PDB link|1PE9, PDB link|1PLU, PDB link|1R76, PDB link|1RU4, PDB link|1VBL, PDB link|2BSP, PDB link|2EWE, PDB link|2PEC, PDB link|2V8I, PDB link|2V8J, and PDB link|2V8K.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9015-75-2."

Gene Ontology (GO) codes