CDP-glucose 4,6-dehydratase

In enzymology, a CDP-glucose 4,6-dehydratase (EC number|4.2.1.45) is an enzyme that catalyzes the chemical reaction

:CDP-glucose $ightleftharpoons$ CDP-4-dehydro-6-deoxy-D-glucose + H₂O

Hence, this enzyme has one substrate, CDP-glucose, and two products, CDP-4-dehydro-6-deoxy-D-glucose and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming). Other names in common use include cytidine diphosphoglucose oxidoreductase, and CDP-glucose 4,6-hydro-lyase. This enzyme participates in starch and sucrose metabolism. It employs one cofactor, NAD+.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1RKX and PDB link|1WVG.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37259-55-5."

Gene Ontology (GO) codes