Cryopyrin

Cryopyrin

Cryopyrin is a recently discovered protein contained in the intracellular inflammasome. This protein has been linked to the pathogenesis of pseudogout, gout, familial mediterranean fever, NOMID (neonatal onset multisystem inflammatory disease) among other conditions.

ee also

* CIAS1


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  • cryopyrin-associated periodic syndrome — any in a group of autoinflammatory diseases caused by mutations in the gene that codes for cryopyrin, resulting in fever, arthralgia, urticaria, and inflammation. Called also cryopyrinopathy …   Medical dictionary

  • cryopyrin — noun A nucleotide binding and leucin rich protein which activates the inflammasome in response to toxins …   Wiktionary

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