Homoglutathione synthase

In enzymology, a homoglutathione synthase (EC number|6.3.2.23) is an enzyme that catalyzes the chemical reaction

:ATP + gamma-L-glutamyl-L-cysteine + beta-alanine $ightleftharpoons$ ADP + phosphate + gamma-L-glutamyl-L-cysteinyl-beta-alanine

The 3 substrates of this enzyme are ATP, gamma-L-glutamyl-L-cysteine, and beta-alanine, whereas its 3 products are ADP, phosphate, and gamma-L-glutamyl-L-cysteinyl-beta-alanine.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming). Other names in common use include homoglutathione synthetase, and beta-alanine specific hGSH synthetase.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|113875-72-2."

Gene Ontology (GO) codes