Chembox new
ImageFile = Tagatose.png ImageSize =
IUPACName = ("3S,4S,5R")-1,3,4,5,6-Pentahydroxy-hexan-2-one
OtherNames =
Section1 = Chembox Identifiers
CASNo = 17598-81-1
PubChem =
SMILES = OC [C@@H] (O) [C@H] (O) [C@H] (O)C(CO)=O

Section2 = Chembox Properties
Formula = C6H12O6
MolarMass = 180.16 g/mol
Appearance = White solid
Density =
MeltingPt = 133-135 °C
BoilingPt =
Solubility =

Section3 = Chembox Hazards
MainHazards =
FlashPt =
Autoignition =

Tagatose is a functional sweetener. It is a naturally occurring monosaccharide, specifically a hexose. It is often found in dairy products, and is very similar in texture to sucrose (table sugar) and is 92% as sweet, but with only 38% of the calories.

Tagatose is generally recognized as safe (GRAS) by the FAO/WHO and has been since 2001.

Since it is metabolized differently from sucrose, tagatose has a minimal effect on blood glucose and insulin levels. Tagatose is also approved as a toothfriendly ingredient.


Tagatose is present in only small amounts in dairy products. It can be produced commercially from lactose, which is first hydrolyzed to glucose and galactose. The galactose is isomerized under alkaline conditions to D-tagatose by calcium hydroxide. The resulting mixture can then be purified and solid tagatose produced by crystallization.

Development as a sweetener

Gilbert Levin upon learning about chirality, had the idea to search for a left-handed sugar. Cycling through the various left-handed sugars, he was accidentally sent D-tagatose, structurally similar to L-fructose. Even though Levin thought that his answer to a sweetener would be found in a left-handed sugar, it was the right-handed molecular form that proved to be a winner.FDA approved tagatose as a food additive in October 2003.


In 1996, MD/Arla Foods acquired the rights to production from Spherix, the American license holder. In the following years, no products were brought to market by MD/Arla Foods and so Spherix brought them before the US Court of Arbitration for showing insufficient interest in bringing the product to market. The companies settled, with MD/Arla Foods agreeing to pay longer term royalties to Spherix and Spherix agreeing to not take further action.

In March 2006, SweetGredients (a joint venture company of Arla Foods and Nordzucker AG) decided to put the tagatose project ”on hold”. SweetGredients was the only worldwide producer of tagatose. While progress has been made in creating a market for this innovative sweetener, it has not been possible to identify a large enough potential justifying continued investments and SweetGredients has decided to close down the manufacturing of tagatose in Nordstemmen, Germany.

In 2006, the Belgian Company NUTRILAB NV took over the Arla (Sweetgredients) stocks and project and is setting up a production site for D-Tagatose with the brandname Nutrilatose, with an enzymatic process method (different from the already published patents). Damhert N.V., the mothercompany of Nutrilab has released the tagatose based sweetener Tagatesse under its own brand name, along with some other products (jams and some chocolate based products) based on tagatose in October 2007 in The Benelux and France.

Products using tagatose

* 7-Eleven's Diet Pepsi flavored Slurpee
* Miada Chocolite
* Pasco Light & Tasty Juice
* Shugr by Swiss Diet
* SweetFiber by Dr. Murray Natural Living
* Therasweet by Living Fuel

External links

* [http://www.wired.com/wired/archive/11.11/newsugar.html Wired Article]
* [http://www.foodnavigator.com/news/news-NG.asp?n=41021-fao-who-recommends FAO/WHO Recommendation]
* [http://www.caloriecontrol.org/tagatose.html Calorie Control Council] -- consumer info from artificial sweetener manufacturers organization
* [http://www.arlafoods.com/appl/HJ/HJ202COM/HJ202D01.NSF/O/20B181DBD7A1F5ACC1257068003EA894 MD/Arla Foods settlement with Spherix]

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Look at other dictionaries:

  • Tagatose — Structure linéaire du D (–) Tagatose L (+) Tagatose Général Nom IUPAC (3S,4S …   Wikipédia en Français

  • tagatose — [tagatoz] n. f. ÉTYM. Mil. XXe; probablt angl. tagatose (in Webster); altér. de galactose, premier élément obscur. ❖ ♦ Chim., biol. Isomère du fructose contenu dans diverses gommes végétales (notamment le Sterculia setigera, arbre africain) …   Encyclopédie Universelle

  • Tagatose — Strukturformel Fischer Projektion, offenkettige Darstellung Allgemeines Name …   Deutsch Wikipedia

  • tagatose — A ketohexose; d t. is epimeric with d fructose. * * * tag·a·tose tag ə .tōsalso .tōz n a crystalline ketohexose sugar C6H12O6 found naturally in the D form (as in gum from a West African tree Sterculia setigera and in various dairy products) and… …   Medical dictionary

  • tagatose — tagatozė statusas T sritis chemija apibrėžtis Ketoheksozė. formulė HOCH₂CO(CHOH)₄H atitikmenys: angl. tagatose rus. тагатоза …   Chemijos terminų aiškinamasis žodynas

  • tagatose — noun The ketohexose (3S,4S,5R) 1,3,4,5,6 pentahydroxy hexan 2 one; it is very sweet …   Wiktionary

  • Tagatose — Ta|ga|to|se [vermutlich anagrammatisch aus Galaktose (wegen der Herst.); ↑ ose (1)], die; , n; Symbol: Tag; systematisches Syn.: lyxo Hex 2 ulose: seltene Ketohexose aus Pflanzengummen …   Universal-Lexikon

  • tagatose — tag·a·tose …   English syllables

  • tagatose — ˈtagəˌtōs also ōz noun ( s) Etymology: alteration of galactose : a crystalline sugar C6H12O6 of the ketohexose class found naturally in the d form (as in gum from a West African tree Sterculia setigera) and also obtainable from galactose by… …   Useful english dictionary

  • Tagatose kinase — In enzymology, a tagatose kinase (EC number| is an enzyme that catalyzes the chemical reaction:ATP + D tagatose ightleftharpoons ADP + D tagatose 6 phosphateThus, the two substrates of this enzyme are ATP and D tagatose, whereas its two …   Wikipedia

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