Beta-lysine 5,6-aminomutase

Beta-lysine 5,6-aminomutase

In enzymology, a beta-lysine 5,6-aminomutase (EC number|5.4.3.3) is an enzyme that catalyzes the chemical reaction

:(3S)-3,6-diaminohexanoate ightleftharpoons (3S,5S)-3,5-diaminohexanoate

Hence, this enzyme has one substrate, (3S)-3,6-diaminohexanoate, and one product, (3S,5S)-3,5-diaminohexanoate.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring amino groups. The systematic name of this enzyme class is (3S)-3,6-diaminohexanoate 5,6-aminomutase. Other names in common use include beta-lysine mutase, and L-beta-lysine 5,6-aminomutase. This enzyme participates in lysine degradation. It employs one cofactor, cobamide.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|1XRS.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9075-69-8."

Gene Ontology (GO) codes


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  • Lysine 2,3-aminomutase — General Reaction= Lysine 2,3 aminomutase (KAM or LAM) (EC [http://www.expasy.org/enzyme/5.4.3.2 |5.4.3.2] ) is an enzyme which facilitates the conversion of the amino acid Lysine to Beta Lysine. It accomplishes this interconversion using three… …   Wikipedia

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