LDHA

Lactate dehydrogenase A, also known as LDHA, is a human gene.

PBB_Summary
section_title =
summary_text = Lactate dehydrogenase A catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria.cite web | title = Entrez Gene: LDHA lactate dehydrogenase A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3939| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Miyajima H, Shimizu T, Kaneko E |title= [Gene expression in lactate dehydrogenase-A subunit deficiency] |journal=Rinsho Shinkeigaku |volume=32 |issue= 10 |pages= 1087–92 |year= 1993 |pmid= 1297552 |doi=
*cite journal | author=Sudo K, Maekawa M, Shioya M, "et al." |title=Molecular analysis of genetic mutation in electrophoretic variant of human lactate dehydrogenase-A(M) subunit. |journal=Biochem. Int. |volume=27 |issue= 6 |pages= 1051–7 |year= 1992 |pmid= 1445373 |doi=
*cite journal | author=Maekawa M, Sudo K, Li SS, Kanno T |title=Analysis of genetic mutations in human lactate dehydrogenase-A(M) deficiency using DNA conformation polymorphism in combination with polyacrylamide gradient gel and silver staining. |journal=Biochem. Biophys. Res. Commun. |volume=180 |issue= 2 |pages= 1083–90 |year= 1991 |pmid= 1953713 |doi=
*cite journal | author=Maekawa M, Sudo K, Li SS, Kanno T |title=Genotypic analysis of families with lactate dehydrogenase A (M) deficiency by selective DNA amplification. |journal=Hum. Genet. |volume=88 |issue= 1 |pages= 34–8 |year= 1992 |pmid= 1959923 |doi=
*cite journal | author=Scrable HJ, Johnson DK, Rinchik EM, Cavenee WK |title=Rhabdomyosarcoma-associated locus and MYOD1 are syntenic but separate loci on the short arm of human chromosome 11. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 6 |pages= 2182–6 |year= 1990 |pmid= 2315312 |doi=
*cite journal | author=Maekawa M, Sudo K, Kanno T, Li SS |title=Molecular characterization of genetic mutation in human lactate dehydrogenase-A (M) deficiency. |journal=Biochem. Biophys. Res. Commun. |volume=168 |issue= 2 |pages= 677–82 |year= 1990 |pmid= 2334430 |doi=
*cite journal | author=Gosti F, Marty MC, Courvalin JC, "et al." |title=Centrosomal proteins and lactate dehydrogenase possess a common epitope in human cell lines. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 4 |pages= 1000–4 |year= 1987 |pmid= 2434947 |doi=
*cite journal | author=Chung FZ, Tsujibo H, Bhattacharyya U, "et al." |title=Genomic organization of human lactate dehydrogenase-A gene. |journal=Biochem. J. |volume=231 |issue= 3 |pages= 537–41 |year= 1986 |pmid= 3000353 |doi=
*cite journal | author=Tsujibo H, Tiano HF, Li SS |title=Nucleotide sequences of the cDNA and an intronless pseudogene for human lactate dehydrogenase-A isozyme. |journal=Eur. J. Biochem. |volume=147 |issue= 1 |pages= 9–15 |year= 1985 |pmid= 3838278 |doi=
*cite journal | author=Glass RD, Doyle D |title=Genetic control of lactate dehydrogenase expression in mammalian tissues. |journal=Science |volume=176 |issue= 31 |pages= 180–1 |year= 1972 |pmid= 5014440 |doi=
*cite journal | author=Maekawa M, Sudo K, Kobayashi A, "et al." |title=Fast-type electrophoretic variant of lactate dehydrogenase M(A) and comparison with other missense mutations in lactate dehydrogenase M(A) and H(B) genes. |journal=Clin. Chem. |volume=40 |issue= 4 |pages= 665–8 |year= 1994 |pmid= 7908613 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Miyajima H, Takahashi Y, Suzuki M, "et al." |title=Molecular characterization of gene expression in human lactate dehydrogenase-A deficiency. |journal=Neurology |volume=43 |issue= 7 |pages= 1414–9 |year= 1993 |pmid= 8327147 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Scanlan MJ, Gordan JD, Williamson B, "et al." |title=Antigens recognized by autologous antibody in patients with renal-cell carcinoma. |journal=Int. J. Cancer |volume=83 |issue= 4 |pages= 456–64 |year= 1999 |pmid= 10508479 |doi=
*cite journal | author=Vilà MR, Nicolás A, Morote J, "et al." |title=Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction. |journal=Cancer |volume=89 |issue= 1 |pages= 152–64 |year= 2000 |pmid= 10897012 |doi=
*cite journal | author=Boutet A, Altmeyer R, Héry C, Tardieu M |title=Direct role of plasma membrane-expressed gp120/41 in toxicity to human astrocytes induced by HIV-1-infected macrophages. |journal=AIDS |volume=14 |issue= 17 |pages= 2687–97 |year= 2001 |pmid= 11125887 |doi=
*cite journal | author=Read JA, Winter VJ, Eszes CM, "et al." |title=Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase. |journal=Proteins |volume=43 |issue= 2 |pages= 175–85 |year= 2001 |pmid= 11276087 |doi=
*cite journal | author=Sung JH, Shin SA, Park HK, "et al." |title=Protective effect of glutathione in HIV-1 lytic peptide 1-induced cell death in human neuronal cells. |journal=J. Neurovirol. |volume=7 |issue= 5 |pages= 454–65 |year= 2001 |pmid= 11582518 |doi=
*cite journal | author=Pioli PA, Hamilton BJ, Connolly JE, "et al." |title=Lactate dehydrogenase is an AU-rich element-binding protein that directly interacts with AUF1. |journal=J. Biol. Chem. |volume=277 |issue= 38 |pages= 35738–45 |year= 2002 |pmid= 12107167 |doi= 10.1074/jbc.M204002200

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