GOLGA2

GOLGA2

Golgi autoantigen, golgin subfamily a, 2, also known as GOLGA2, is a human gene.

PBB_Summary
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summary_text = The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The golgins are a family of proteins, of which the protein encoded by this gene is a member, that are localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined.cite web | title = Entrez Gene: GOLGA2 golgi autoantigen, golgin subfamily a, 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2801| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Fritzler MJ, Hamel JC, Ochs RL, Chan EK |title=Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex. |journal=J. Exp. Med. |volume=178 |issue= 1 |pages= 49–62 |year= 1993 |pmid= 8315394 |doi=
*cite journal | author=Nakamura N, Rabouille C, Watson R, "et al." |title=Characterization of a cis-Golgi matrix protein, GM130. |journal=J. Cell Biol. |volume=131 |issue= 6 Pt 2 |pages= 1715–26 |year= 1996 |pmid= 8557739 |doi=
*cite journal | author=Nakamura N, Lowe M, Levine TP, "et al." |title=The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner. |journal=Cell |volume=89 |issue= 3 |pages= 445–55 |year= 1997 |pmid= 9150144 |doi=
*cite journal | author=Barr FA, Puype M, Vandekerckhove J, Warren G |title=GRASP65, a protein involved in the stacking of Golgi cisternae. |journal=Cell |volume=91 |issue= 2 |pages= 253–62 |year= 1997 |pmid= 9346242 |doi=
*cite journal | author=Sohda M, Misumi Y, Yano A, "et al." |title=Phosphorylation of the vesicle docking protein p115 regulates its association with the Golgi membrane. |journal=J. Biol. Chem. |volume=273 |issue= 9 |pages= 5385–8 |year= 1998 |pmid= 9478999 |doi=
*cite journal | author=Barr FA, Nakamura N, Warren G |title=Mapping the interaction between GRASP65 and GM130, components of a protein complex involved in the stacking of Golgi cisternae. |journal=EMBO J. |volume=17 |issue= 12 |pages= 3258–68 |year= 1998 |pmid= 9628863 |doi= 10.1093/emboj/17.12.3258
*cite journal | author=Lowe M, Rabouille C, Nakamura N, "et al." |title=Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis. |journal=Cell |volume=94 |issue= 6 |pages= 783–93 |year= 1998 |pmid= 9753325 |doi=
*cite journal | author=Barr FA |title=A novel Rab6-interacting domain defines a family of Golgi-targeted coiled-coil proteins. |journal=Curr. Biol. |volume=9 |issue= 7 |pages= 381–4 |year= 1999 |pmid= 10209123 |doi=
*cite journal | author=Shorter J, Watson R, Giannakou ME, "et al." |title=GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system. |journal=EMBO J. |volume=18 |issue= 18 |pages= 4949–60 |year= 1999 |pmid= 10487747 |doi= 10.1093/emboj/18.18.4949
*cite journal | author=Bouchireb N, Clark MS |title=Human golgin-95 gene (GOLGA2). Map position 9q32-34.1. |journal=Chromosome Res. |volume=7 |issue= 6 |pages= 501 |year= 1999 |pmid= 10560974 |doi=
*cite journal | author=Linstedt AD, Jesch SA, Mehta A, "et al." |title=Binding relationships of membrane tethering components. The giantin N terminus and the GM130 N terminus compete for binding to the p115 C terminus. |journal=J. Biol. Chem. |volume=275 |issue= 14 |pages= 10196–201 |year= 2000 |pmid= 10744704 |doi=
*cite journal | author=Lowe M, Gonatas NK, Warren G |title=The mitotic phosphorylation cycle of the cis-Golgi matrix protein GM130. |journal=J. Cell Biol. |volume=149 |issue= 2 |pages= 341–56 |year= 2000 |pmid= 10769027 |doi=
*cite journal | author=Alvarez C, Garcia-Mata R, Hauri HP, Sztul E |title=The p115-interactive proteins GM130 and giantin participate in endoplasmic reticulum-Golgi traffic. |journal=J. Biol. Chem. |volume=276 |issue= 4 |pages= 2693–700 |year= 2001 |pmid= 11035033 |doi= 10.1074/jbc.M007957200
*cite journal | author=Moyer BD, Allan BB, Balch WE |title=Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis--Golgi tethering. |journal=Traffic |volume=2 |issue= 4 |pages= 268–76 |year= 2001 |pmid= 11285137 |doi=
*cite journal | author=Weide T, Bayer M, Köster M, "et al." |title=The Golgi matrix protein GM130: a specific interacting partner of the small GTPase rab1b. |journal=EMBO Rep. |volume=2 |issue= 4 |pages= 336–41 |year= 2001 |pmid= 11306556 |doi= 10.1093/embo-reports/kve065
*cite journal | author=Puthenveedu MA, Linstedt AD |title=Evidence that Golgi structure depends on a p115 activity that is independent of the vesicle tether components giantin and GM130. |journal=J. Cell Biol. |volume=155 |issue= 2 |pages= 227–38 |year= 2001 |pmid= 11591729 |doi= 10.1083/jcb.200105005
*cite journal | author=Miles S, McManus H, Forsten KE, Storrie B |title=Evidence that the entire Golgi apparatus cycles in interphase HeLa cells: sensitivity of Golgi matrix proteins to an ER exit block. |journal=J. Cell Biol. |volume=155 |issue= 4 |pages= 543–55 |year= 2001 |pmid= 11696556 |doi= 10.1083/jcb.200103104
*cite journal | author=Majoul I, Straub M, Hell SW, "et al." |title=KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET. |journal=Dev. Cell |volume=1 |issue= 1 |pages= 139–53 |year= 2001 |pmid= 11703931 |doi=
*cite journal | author=Valsdottir R, Hashimoto H, Ashman K, "et al." |title=Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER. |journal=FEBS Lett. |volume=508 |issue= 2 |pages= 201–9 |year= 2001 |pmid= 11718716 |doi=
*cite journal | author=Short B, Preisinger C, Körner R, "et al." |title=A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic. |journal=J. Cell Biol. |volume=155 |issue= 6 |pages= 877–83 |year= 2002 |pmid= 11739401 |doi= 10.1083/jcb.200108079

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