ICAM2

Intercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a human gene.

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.cite web | title = Entrez Gene: ICAM2 intercellular adhesion molecule 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3384| accessdate = ]

ee also

* Cluster of differentiation

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Simmons DL |title=The role of ICAM expression in immunity and disease. |journal=Cancer Surv. |volume=24 |issue= |pages= 141–55 |year= 1995 |pmid= 7553659 |doi=
*cite journal | author=Hayflick JS, Kilgannon P, Gallatin WM |title=The intercellular adhesion molecule (ICAM) family of proteins. New members and novel functions. |journal=Immunol. Res. |volume=17 |issue= 3 |pages= 313–27 |year= 1998 |pmid= 9638475 |doi=
*cite journal | author=Lalor PF, Shields P, Grant A, Adams DH |title=Recruitment of lymphocytes to the human liver. |journal=Immunol. Cell Biol. |volume=80 |issue= 1 |pages= 52–64 |year= 2002 |pmid= 11869363 |doi=
*cite journal | author=Yonekawa K, Harlan JM |title=Targeting leukocyte integrins in human diseases. |journal=J. Leukoc. Biol. |volume=77 |issue= 2 |pages= 129–40 |year= 2005 |pmid= 15548573 |doi= 10.1189/jlb.0804460
*cite journal | author=de Fougerolles AR, Stacker SA, Schwarting R, Springer TA |title=Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1. |journal=J. Exp. Med. |volume=174 |issue= 1 |pages= 253–67 |year= 1991 |pmid= 1676048 |doi=
*cite journal | author=Sansom D, Borrow J, Solomon E, Trowsdale J |title=The human ICAM2 gene maps to 17q23-25. |journal=Genomics |volume=11 |issue= 2 |pages= 462–4 |year= 1992 |pmid= 1769660 |doi=
*cite journal | author=Staunton DE, Dustin ML, Springer TA |title=Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. |journal=Nature |volume=339 |issue= 6219 |pages= 61–4 |year= 1989 |pmid= 2497351 |doi= 10.1038/339061a0
*cite journal | author=Bujía J, Holly A, Kim C, "et al." |title=Expression of human intercellular adhesion molecules in middle ear cholesteatoma. |journal=Am J Otolaryngol |volume=15 |issue= 4 |pages= 271–5 |year= 1994 |pmid= 7526720 |doi=
*cite journal | author=de Fougerolles AR, Qin X, Springer TA |title=Characterization of the function of intercellular adhesion molecule (ICAM)-3 and comparison with ICAM-1 and ICAM-2 in immune responses. |journal=J. Exp. Med. |volume=179 |issue= 2 |pages= 619–29 |year= 1994 |pmid= 7905020 |doi=
*cite journal | author=Butini L, De Fougerolles AR, Vaccarezza M, "et al." |title=Intercellular adhesion molecules (ICAM)-1 ICAM-2 and ICAM-3 function as counter-receptors for lymphocyte function-associated molecule 1 in human immunodeficiency virus-mediated syncytia formation. |journal=Eur. J. Immunol. |volume=24 |issue= 9 |pages= 2191–5 |year= 1994 |pmid= 7916296 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Hirao M, Sato N, Kondo T, "et al." |title=Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. |journal=J. Cell Biol. |volume=135 |issue= 1 |pages= 37–51 |year= 1996 |pmid= 8858161 |doi=
*cite journal | author=Bernstein CN, Sargent M, Gallatin WM, Wilkins J |title=Beta 2-integrin/intercellular adhesion molecule (ICAM) expression in the normal human intestine. |journal=Clin. Exp. Immunol. |volume=106 |issue= 1 |pages= 160–9 |year= 1996 |pmid= 8870715 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Casasnovas JM, Springer TA, Liu JH, "et al." |title=Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface. |journal=Nature |volume=387 |issue= 6630 |pages= 312–5 |year= 1997 |pmid= 9153399 |doi= 10.1038/387312a0
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Sainio M, Zhao F, Heiska L, "et al." |title=Neurofibromatosis 2 tumor suppressor protein colocalizes with ezrin and CD44 and associates with actin-containing cytoskeleton. |journal=J. Cell. Sci. |volume=110 ( Pt 18) |issue= |pages= 2249–60 |year= 1997 |pmid= 9378774 |doi=
*cite journal | author=Yonemura S, Hirao M, Doi Y, "et al." |title=Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. |journal=J. Cell Biol. |volume=140 |issue= 4 |pages= 885–95 |year= 1998 |pmid= 9472040 |doi=
*cite journal | author=Bernstein CN, Sargent M, Gallatin WM |title=Beta2 integrin/ICAM expression in Crohn's disease. |journal=Clin. Immunol. Immunopathol. |volume=86 |issue= 2 |pages= 147–60 |year= 1998 |pmid= 9473377 |doi=

External links

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