- HIST4H4
Histone cluster 4, H4, also known as HIST4H4, is a human
gene .PBB_Summary
section_title =
summary_text = Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.cite web | title = Entrez Gene: HIST4H4 histone cluster 4, H4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=121504| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Pauli U, Chrysogelos S, Stein G, "et al." |title=Protein-DNA interactions in vivo upstream of a cell cycle-regulated human H4 histone gene. |journal=Science |volume=236 |issue= 4806 |pages= 1308–11 |year= 1987 |pmid= 3035717 |doi=10.1126/science.3035717
*cite journal | author=Borowski P, Heiland M, Oehlmann K, "et al." |title=Non-structural protein 3 of hepatitis C virus inhibits phosphorylation mediated by cAMP-dependent protein kinase. |journal=Eur. J. Biochem. |volume=237 |issue= 3 |pages= 611–8 |year= 1996 |pmid= 8647104 |doi=10.1111/j.1432-1033.1996.0611p.x
*cite journal | author=El Kharroubi A, Piras G, Zensen R, Martin MA |title=Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. |journal=Mol. Cell. Biol. |volume=18 |issue= 5 |pages= 2535–44 |year= 1998 |pmid= 9566873 |doi=
*cite journal | author=Zhang Y, Sun ZW, Iratni R, "et al." |title=SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. |journal=Mol. Cell |volume=1 |issue= 7 |pages= 1021–31 |year= 1998 |pmid= 9651585 |doi=10.1016/S1097-2765(00)80102-1
*cite journal | author=Carrier F, Georgel PT, Pourquier P, "et al." |title=Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin. |journal=Mol. Cell. Biol. |volume=19 |issue= 3 |pages= 1673–85 |year= 1999 |pmid= 10022855 |doi=
*cite journal | author=Buggy JJ, Sideris ML, Mak P, "et al." |title=Cloning and characterization of a novel human histone deacetylase, HDAC8. |journal=Biochem. J. |volume=350 Pt 1 |issue= |pages= 199–205 |year= 2001 |pmid= 10926844 |doi=
*cite journal | author=Deng L, de la Fuente C, Fu P, "et al." |title=Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. |journal=Virology |volume=277 |issue= 2 |pages= 278–95 |year= 2001 |pmid= 11080476 |doi= 10.1006/viro.2000.0593
*cite journal | author=Chadwick BP, Willard HF |title=A novel chromatin protein, distantly related to histone H2A, is largely excluded from the inactive X chromosome. |journal=J. Cell Biol. |volume=152 |issue= 2 |pages= 375–84 |year= 2001 |pmid= 11266453 |doi=10.1083/jcb.152.2.375
*cite journal | author=Kovalsky O, Lung FD, Roller PP, Fornace AJ |title=Oligomerization of human Gadd45a protein. |journal=J. Biol. Chem. |volume=276 |issue= 42 |pages= 39330–9 |year= 2001 |pmid= 11498536 |doi= 10.1074/jbc.M105115200
*cite journal | author=Deng L, Wang D, de la Fuente C, "et al." |title=Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA. |journal=Virology |volume=289 |issue= 2 |pages= 312–26 |year= 2001 |pmid= 11689053 |doi= 10.1006/viro.2001.1129
*cite journal | author=Lahn BT, Tang ZL, Zhou J, "et al." |title=Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 13 |pages= 8707–12 |year= 2002 |pmid= 12072557 |doi= 10.1073/pnas.082248899
*cite journal | author=Ono S, Oue N, Kuniyasu H, "et al." |title=Acetylated histone H4 is reduced in human gastric adenomas and carcinomas. |journal=J. Exp. Clin. Cancer Res. |volume=21 |issue= 3 |pages= 377–82 |year= 2003 |pmid= 12385581 |doi=
*cite journal | author=Marzluff WF, Gongidi P, Woods KR, "et al." |title=The human and mouse replication-dependent histone genes. |journal=Genomics |volume=80 |issue= 5 |pages= 487–98 |year= 2003 |pmid= 12408966 |doi=10.1016/S0888-7543(02)96850-3
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kzhyshkowska J, Rusch A, Wolf H, Dobner T |title=Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7. |journal=Biochem. J. |volume=371 |issue= Pt 2 |pages= 385–93 |year= 2003 |pmid= 12489984 |doi= 10.1042/BJ20021281
*cite journal | author=Fujita K, Shimazaki N, Ohta Y, "et al." |title=Terminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histone. |journal=Genes Cells |volume=8 |issue= 6 |pages= 559–71 |year= 2004 |pmid= 12786946 |doi=10.1046/j.1365-2443.2003.00656.x
*cite journal | author=Shiio Y, Eisenman RN |title=Histone sumoylation is associated with transcriptional repression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 23 |pages= 13225–30 |year= 2004 |pmid= 14578449 |doi= 10.1073/pnas.1735528100
*cite journal | author=Coleman MA, Miller KA, Beernink PT, "et al." |title=Identification of chromatin-related protein interactions using protein microarrays. |journal=Proteomics |volume=3 |issue= 11 |pages= 2101–7 |year= 2004 |pmid= 14595808 |doi= 10.1002/pmic.200300593
*cite journal | author=Lusic M, Marcello A, Cereseto A, Giacca M |title=Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. |journal=Embo J. |volume=22 |issue= 24 |pages= 6550–61 |year= 2004 |pmid= 14657027 |doi= 10.1093/emboj/cdg631
*cite journal | author=Kanno T, Kanno Y, Siegel RM, "et al." |title=Selective recognition of acetylated histones by bromodomain proteins visualized in living cells. |journal=Mol. Cell |volume=13 |issue= 1 |pages= 33–43 |year= 2004 |pmid= 14731392 |doi=10.1016/S1097-2765(03)00482-9PBB_Controls
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