- SDC4
Syndecan 4, also known as SDC4, is a human
gene .PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22.cite web | title = Entrez Gene: SDC4 syndecan 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6385| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Bass MD, Humphries MJ |title=Cytoplasmic interactions of syndecan-4 orchestrate adhesion receptor and growth factor receptor signalling. |journal=Biochem. J. |volume=368 |issue= Pt 1 |pages= 1–15 |year= 2002 |pmid= 12241528 |doi= 10.1042/BJ20021228
*cite journal | author=David G, van der Schueren B, Marynen P, "et al." |title=Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells. |journal=J. Cell Biol. |volume=118 |issue= 4 |pages= 961–9 |year= 1992 |pmid= 1500433 |doi=
*cite journal | author=Yu H, Humphries DE, Watkins M, Karlinsky JB |title=Molecular cloning of the human ryudocan promoter. |journal=Biochem. Biophys. Res. Commun. |volume=212 |issue= 3 |pages= 1139–44 |year= 1995 |pmid= 7626103 |doi=
*cite journal | author=Barillari G, Gendelman R, Gallo RC, Ensoli B |title=The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 17 |pages= 7941–5 |year= 1993 |pmid= 7690138 |doi=
*cite journal | author=Kojima T, Inazawa J, Takamatsu J, "et al." |title=Human ryudocan core protein: molecular cloning and characterization of the cDNA, and chromosomal localization of the gene. |journal=Biochem. Biophys. Res. Commun. |volume=190 |issue= 3 |pages= 814–22 |year= 1993 |pmid= 7916598 |doi= 10.1006/bbrc.1993.1122
*cite journal | author=Woods A, Couchman JR |title=Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component. |journal=Mol. Biol. Cell |volume=5 |issue= 2 |pages= 183–92 |year= 1994 |pmid= 8019004 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Albini A, Benelli R, Presta M, "et al." |title=HIV-tat protein is a heparin-binding angiogenic growth factor. |journal=Oncogene |volume=12 |issue= 2 |pages= 289–97 |year= 1996 |pmid= 8570206 |doi=
*cite journal | author=Kojima T, Katsumi A, Yamazaki T, "et al." |title=Human ryudocan from endothelium-like cells binds basic fibroblast growth factor, midkine, and tissue factor pathway inhibitor. |journal=J. Biol. Chem. |volume=271 |issue= 10 |pages= 5914–20 |year= 1996 |pmid= 8621465 |doi=
*cite journal | author=Takagi A, Kojima T, Tsuzuki S, "et al." |title=Structural organization and promoter activity of the human ryudocan gene. |journal=J. Biochem. |volume=119 |issue= 5 |pages= 979–84 |year= 1997 |pmid= 8797100 |doi=
*cite journal | author=Rusnati M, Coltrini D, Oreste P, "et al." |title=Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size. |journal=J. Biol. Chem. |volume=272 |issue= 17 |pages= 11313–20 |year= 1997 |pmid= 9111037 |doi=
*cite journal | author=Chang HC, Samaniego F, Nair BC, "et al." |title=HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region. |journal=AIDS |volume=11 |issue= 12 |pages= 1421–31 |year= 1997 |pmid= 9342064 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Horowitz A, Simons M |title=Regulation of syndecan-4 phosphorylation in vivo. |journal=J. Biol. Chem. |volume=273 |issue= 18 |pages= 10914–8 |year= 1998 |pmid= 9556568 |doi=
*cite journal | author=Lee D, Oh ES, Woods A, "et al." |title=Solution structure of a syndecan-4 cytoplasmic domain and its interaction with phosphatidylinositol 4,5-bisphosphate. |journal=J. Biol. Chem. |volume=273 |issue= 21 |pages= 13022–9 |year= 1998 |pmid= 9582338 |doi=
*cite journal | author=Cohen AR, Woods DF, Marfatia SM, "et al." |title=Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells. |journal=J. Cell Biol. |volume=142 |issue= 1 |pages= 129–38 |year= 1998 |pmid= 9660868 |doi=
*cite journal | author=Rusnati M, Tulipano G, Spillmann D, "et al." |title=Multiple interactions of HIV-I Tat protein with size-defined heparin oligosaccharides. |journal=J. Biol. Chem. |volume=274 |issue= 40 |pages= 28198–205 |year= 1999 |pmid= 10497173 |doi=
*cite journal | author=Gao Y, Li M, Chen W, Simons M |title=Synectin, syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration. |journal=J. Cell. Physiol. |volume=184 |issue= 3 |pages= 373–9 |year= 2000 |pmid= 10911369 |doi= 10.1002/1097-4652(200009)184:3<373::AID-JCP12>3.0.CO;2-I |doilabel=10.1002/1097-4652(200009)184:3373::AID-JCP123.0.CO;2-I
*cite journal | author=Tyagi M, Rusnati M, Presta M, Giacca M |title=Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans. |journal=J. Biol. Chem. |volume=276 |issue= 5 |pages= 3254–61 |year= 2001 |pmid= 11024024 |doi= 10.1074/jbc.M006701200
*cite journal | author=Shin J, Lee W, Lee D, "et al." |title=Solution structure of the dimeric cytoplasmic domain of syndecan-4. |journal=Biochemistry |volume=40 |issue= 29 |pages= 8471–8 |year= 2001 |pmid= 11456484 |doi=PBB_Controls
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