Estradiol 6beta-monooxygenase

In enzymology, an estradiol 6beta-monooxygenase (EC number|1.14.99.11) is an enzyme that catalyzes the chemical reaction

:estradiol-17beta + AH₂ + O₂ $ightleftharpoons$ 6beta-hydroxyestradiol-17beta + A + H₂O

The 3 substrates of this enzyme are estradiol-17beta, AH2, and O₂, whereas its 3 products are 6beta-hydroxyestradiol-17beta, A, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating). This enzyme is also called estradiol 6beta-hydroxylase. This enzyme participates in androgen and estrogen metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9029-70-3."

Gene Ontology (GO) codes