Isabel Riquelme

Infobox Person
name=Isabel Riquelme

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caption=
birth_date=1758/1759
dead=dead
birth_place=Chillán, Chile
death_date=April 21, 1839
death_place=Lima, Peru

María Isabel Riquelme de la Barrera y Meza (b. 1758-April 21, 1839), was the mother of Chilean independence leader Bernardo O'Higgins.

She was born in Chillán, the second daughter of Simón Riquelme de la Barrera Goycochea and of María Mercedes de Mesa y Ulloa. At the age of 16, she became pregnant by Ambrosio O'Higgins, Marquis of Osorno, future viceroy of Peru.

She married twice, firstly in 1780 to Félix Rodríguez Rojas, by whom she had a daughter Rosa Rodríguez Riquelme (Chillán, August 30, 1781 – Lima, 1850). Her husband died in 1782 and she married secondly to Manuel de Puga y Figueroa, by whom she had another daughter named Maria de las Nieves de Puga Riquelme in 1793.