7-PET

7-PET

drugbox



IUPAC_name = 7- [1-phenyl-3-hydroxybut-3-yl] endoethenotetrahydrothebaine
PubChem =
C = 31 | H = 39 | N = 1 | O = 4
molecular_weight = 487.64 g/mol
CAS_number =
legal_status =

7-PET is a potent analgesic drug, several thousand times stronger than morphine by weight. It is related to the more well-known oripavine derivative opioid etorphine, which is used as a very potent veterinary painkiller and anesthetic medication, used primarily for the sedation of large animals such as elephants, giraffes and rhinos. 7-PET is around the same potency as etorphine as a μ agonist. [Feinberg AP, Creese I, Snyder SH. The opiate receptor: a model explaining structure-activity relationships of opiate agonists and antagonists. "Proceedings of the National Academy of Sciences U S A". 1976 Nov;73(11):4215-9.] [Bentley KW, Lewis JW. Agonist and Antagonist Actions of Narcotic Analgesic Drugs. pp 7-16. University Park Press, Baltimore. (1973)]

Unlike etorphine however, 7-PET is not an illegal drug, and is not controlled under the UN drug conventions, but it might still be considered to be a controlled substance analogue of etorphine on the grounds of its related chemical structure in some jurisdictions such as the USA, Canada, Australia and New Zealand.

References


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