- 3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase
In
enzymology , a 3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase (EC number|1.1.1.152) is anenzyme that catalyzes thechemical reaction :3alpha-hydroxy-5beta-androstane-17-one + NAD+ 5beta-androstane-3,17-dione + NADH + H+
Thus, the two substrates of this enzyme are
3alpha-hydroxy-5beta-androstane-17-one and NAD+, whereas its 3 products are5beta-androstane-3,17-dione , NADH, and H+.This enzyme belongs to the family of
oxidoreductase s, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase. Other names in common use include etiocholanolone 3alpha-dehydrogenase, etiocholanolone 3alpha-dehydrogenase, and 3alpha-hydroxy-5beta-steroid dehydrogenase. This enzyme participates inandrogen and estrogen metabolism .References
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External links
::"The
CAS registry number for this enzyme class is CAS registry|37250-77-4."Gene Ontology (GO) codes
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