Macrogol

Macrogol

Drugbox
IUPAC_name = N-(2-diethylaminoethyl)-1-benzothiophene-2-carboxamide

|200px
CAS_number =
ATC_prefix = A06
ATC_suffix = AD15
PubChem = 27175
DrugBank =
chemical_formula = C15H20N2OS
molecular_weight = 276.3971
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category=
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Macrogol is a laxative.

It has been used to treat constipation.cite journal |author=Zangaglia R, Martignoni E, Glorioso M, "et al" |title=Macrogol for the treatment of constipation in Parkinson's disease. A randomized placebo-controlled study |journal=Mov. Disord. |volume=22 |issue=9 |pages=1239–44 |year=2007 |pmid=17566120 |doi=10.1002/mds.21243]

Types include:
* macrogol 4000cite web |url=http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=27175 |title=CID 27175 -- PubChem Compound Summary |accessdate=2008-01-18 |format= |work=]
* macrogol 3350cite journal |author=Hardikar W, Cranswick N, Heine RG |title=Macrogol 3350 plus electrolytes for chronic constipation in children: a single-centre, open-label study |journal=J Paediatr Child Health |volume=43 |issue=7-8 |pages=527–31 |year=2007 |pmid=17635680 |doi=10.1111/j.1440-1754.2007.01116.x |url=http://www.blackwell-synergy.com/openurl?genre=article&sid=nlm:pubmed&issn=1034-4810&date=2007&volume=43&issue=7-8&spage=527]
* macrogol 6000cite journal |author=Hyry H, Vuorio A, Varjonen E, Skyttä J, Mäkinen-Kiljunen S |title=Two cases of anaphylaxis to macrogol 6000 after ingestion of drug tablets |journal=Allergy |volume=61 |issue=8 |pages=1021 |year=2006 |pmid=16867059 |doi=10.1111/j.1398-9995.2006.01083.x |url=http://www.blackwell-synergy.com/openurl?genre=article&sid=nlm:pubmed&issn=0105-4538&date=2006&volume=61&issue=8&spage=1021]

ee also

* Polyethylene glycol

References


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