Soluble low density lipoprotein receptor-related protein
- Soluble low density lipoprotein receptor-related protein
Soluble low density lipoprotein receptor-related protein (sLRP) is a biological substance naturally produced by the human body. [cite journal | author=Quinn KA, Pye VJ. "et al."| title=Characterization of the soluble form of the low density lipoprotein receptor-related protein (LRP) | journal =Exp. Cell Res. | year=1999 | volume=251 | issue=2 | pages=433–441 | pmid = 10471328| doi=10.1006/excr.1999.4590] [cite journal | author=Quinn KA, Grimsley PG, "et al."| title=Soluble low density lipoprotein receptor-related protein (LRP) circulates in human plasma | journal =J. Biol. Chem. | year=1997 | volume=272 | issue=38 | pages=23946–23951 | pmid = 9295345| doi=10.1074/jbc.272.38.23946] This protein has been found to bind to and neutralize anywhere from 70 to 90 percent of the amyloid-beta peptide that also naturally circulates in healthy human or mouse plasma. [cite web | title = Draining away brain's toxic protein to stop Alzheimer's | url = http://www.eurekalert.org/pub_releases/2007-08/uorm-dab080907.php | accessdate = 2007-10-25] Impairment of this function is strongly associated with, and may soon be shown definitively to be the principal cause of, Alzheimer's Disease. [cite journal | author=Sagare A, Deane R. "et al."| title=Clearance of amyloid-beta by circulating lipoprotein receptors. | journal =Nat. Med. | year=2007 | volume=13 | issue=9 | pages=1029–1031 | pmid = 17694066| doi=10.1038/nm1635]
References
Wikimedia Foundation.
2010.
Look at other dictionaries:
Low density lipoprotein receptor-related protein 8 — Low density lipoprotein receptor related protein 8, apolipoprotein e receptor, also known as LRP8, is a human gene.cite web | title = Entrez Gene: LRP8 low density lipoprotein receptor related protein 8, apolipoprotein e receptor| url =… … Wikipedia
Low density lipoprotein receptor gene family — The low density lipoprotein receptor gene family code for a class of structurally closely related cell surface receptors that fulfill diverse biological functions in different organs, tissues, and cell types.cite journal | author = Nykjaer A,… … Wikipedia
Low-density lipoprotein — (LDL) is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. LDL is one of the five major groups of lipoproteins; these groups include chylomicrons, very low density lipoprotein (VLDL),… … Wikipedia
LRP — can refer to:* Lateralized Readiness Potential * Lead Replacement Petrol * League for the Revolutionary Party * The Lesser Ritual of the Pentagram * Lime Rock Park in Connecticut * The Linux Router Project * Lipoprotein receptor related Protein;… … Wikipedia
SLRP — may be an abbreviation for *Soluble low density lipoprotein receptor related protein *Small leucine rich repeat protein *Small leucine rich repeat proteoglycan … Wikipedia
Furin — FUR redirects here. For other uses, see Fur (disambiguation). Furin (paired basic amino acid cleaving enzyme) PDB rendering based on 1p8j … Wikipedia
MMP16 — Matrix metallopeptidase 16 (membrane inserted), also known as MMP16, is a human gene.cite web | title = Entrez Gene: MMP16 matrix metallopeptidase 16 (membrane inserted)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… … Wikipedia
PCSK9 — Proprotein convertase subtilisin/kexin type 9 PDB rendering based on 2p4e … Wikipedia
Mammalian target of rapamycin — Mechanistic target of rapamycin (serine/threonine kinase) PDB rendering based on 1aue … Wikipedia
Apolipoprotein E — (APOE) is an apoprotein found in the chylomicron that binds to a specific receptor on liver cells and peripheral cells. It is essential for the normal catabolism of triglyceride rich lipoprotein constituents.cite web | title = Entrez Gene: APOE… … Wikipedia
