- Tubex
The Tubex Syringe cartridge was developed about 1943 during World War II by the
Wyeth company. It is a drug pre-filled glass cartridgesyringe with attached sterile needle, which is inserted in a reusable stainless steel holder (now plastic). The needle protector is removed and is ready for immediate injection in the administration of a drug.Its development followed the use of several other immediate use products, such as the
Syrette , a flexible tube, not unlike an ophthalmicointment tube designed to hold a needle. The Syrette was developed by Squibb and was used for immediate use ofmorphine on the battle front however it fell into disuse because of leakage and sterility problems. Another product called the Ampin proved problematic as well.The Tubex system was widely used after World War II and expanded as a system of distributing and administration a large variety of drugs from
antibiotic s tovaccine s in a pre-filled glass cartridge syringe with attached sterile needle. It aided in a standardization of an immediate use sterile dosage forms. It was a time saver fornursing administration time, (nurses no longer had to draw up an injection). The product was all ready manufactured for immediate use. It was conducive to inventory control and accountability fornarcotic substances in a tamper proof packing. It was widely used by doctors, nurses andpharmacist s for the administration of drugs. Although a few products are still manufactured in Tubex, the Wyeth company has discontinued the entire line of products and has licensed its use to other companies. [cite book | last =Sterile Dosage Forms | first = | authorlink = | coauthors =Salvatore Turco, M.S., PharmD and Robert E King, Ph.D. | title =Sterile Dosage Forms, Their Preparation and Clinical Application | publisher = Lea & Febiger | date =1987 | location =Philadelphia | pages =267-269 | url = | doi = | id = | isbn = 0-8121-1067-6]References
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