Streptolydigin

drugbox
IUPAC_name = 2- [4- [6-(1,6-dimethylspiro [8,9-dioxabicyclo [3.3.1] non-3-ene-2,2'-oxirane] -7-yl)-4-methylhepta-2,4-dienoyl] -5-hydroxy-1-(5-hydroxy-6-methyloxan-2-yl)-3-oxo-2H-pyrrol-2-yl] -N-methylpropanamide

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CAS_number = 7229-50-7
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PubChem = 220508
DrugBank =
C=32 | H=44 | N=2 | O=9
molecular_weight = 600.708 g/mol
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Streptolydigin is an antibiotic which works by blocking nucleic acid chain elongation by binding to the polymerase, thus stopping RNA polymerase activity inside a cell. Specifically, it inhibits the assembly of the RNA polymerase II transcription complex and DNA polymerase III transcription. It is active against a number of gram positive bacteria.