YybP-ykoY leader

YybP-ykoY leader

The yybP-ykoY leader RNA element was originally discovered in "E. coli" during a large scale screen and was named SraF.cite journal | last = Argaman | first = L | coauthors = Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, Altuvia S | year = 2001 | title = Novel small RNA-encoding genes in the intergenic regions of Escherichia coli | journal = Curr Biol | volume = 11 | pages = 941–950 | pmid = 11448770 | doi = 10.1016/S0960-9822(01)00270-6] This family was later found to exist upstream of related families of protein genes in many bacteria, including the the yybP and ykoY genes in "B. subtilis". The specific functions of these proteins are unknown, but this structured RNA element may be involved in their genetic regulation as a riboswitch.cite journal | last = Barrick | first = JE | coauthors = Corbino KA, Winkler WC, Nahvi A, Mandal M, Collins J, Lee M, Roth A, Sudarsan N, Jona I, Wickiser JK, Breaker RR | year = 2004 | title = New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control | journal = Proc Natl Acad Sci U S A | volume = 101 | pages = 6421–6426 | pmid = 15096624 | doi = 10.1073/pnas.0308014101]

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