Tombus virus defective interfering (DI) RNA region 3

Tombus virus defective interfering (DI) RNA region 3 is an important cis-regulatory region identified in the 3'UTR of Tombus virus defective interfering (DI) particles (DI)cite journal | author = Ray D, White KA | title = An internally located RNA hairpin enhances replication of Tomato bushy stunt virus RNAs | journal = J. Virol. | volume = 77 | issue = 1 | pages = 245–57 | year = 2003 | pmid = 12477830 | doi = ] .

Defective interfering RNAs are small sub-viral replicons which are non-coding deletion mutants of the virus that maintain cis-acting RNA elements necessary for replication of the host virus . This conserved region of the 3'UTR has been found to enhance DI RNA accumulation by approximately 10-fold as well as mediating viral replication.

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