Small nucleolar RNA TBR5

TBR5 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs [1,2] .

References

* [1] cite journal | last = Galardi | first = S | coauthors = Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I | year = 2002 | title = Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro | journal = Mol Cell Biol | volume = 22 | pages = 6663–6668 | pmid = 12215523 | doi = 10.1128/MCB.22.19.6663-6668.2002
* [2] cite journal | last = Dunbar | first = DA | coauthors = Wormsley S, Lowe TM, Baserga SJ | year = 2000 | title = Fibrillarin-associated box C/D small nucleolar RNAs in Trypanosoma brucei. Sequence conservation and implications for 2'-O-ribose methylation of rRNA | journal = J Biol Chem | volume = 275 | pages = 14767–14776 | pmid = 10747997 | doi = 10.1074/jbc.M001180200

External links

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