Small nucleolar RNA SNORD78

U78 belongs to the CD family of snoRNAs. It is predicted to guide 2'O-ribose methylation of the large 28S rRNA subunit at position G4593. [cite journal | last = Tycowski | first = KT | coauthors = Aab A, Steitz JA | year = 2004 | title = Guide RNAs with 5' caps and novel box C/D snoRNA-like domains for modification of snRNAs in metazoa | journal = Curr Biol. | volume = 14 | pages = 1985–1995 | pmid = 15556860 | doi = 10.1016/j.cub.2004.11.003] The snoRNAs U44, U47, U74, U75, U76, U77, U79, U80 and U81, also of the C/D family, share the same host gene with U78 (protein non-coding). [cite journal | last = Lestrade | first = L | coauthors = Weber MJ | year = 2006 | title = snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs | journal = Nucleic Acids Res. | volume = 34 | pages = D158–D162 | pmid = 16381836 | doi = 10.1093/nar/gkj002]

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