Small nucleolar RNA SNORA71

Small nucleolar RNA SNORA71

In molecular biology, U71 belongs to the H/ACA class of Small nucleolar RNA (snoRNAs). snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs. [cite journal | last = Kiss | first = T | year = 2002 | title = Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions | journal = Cell | volume = 109 | pages = 145–148 | pmid = 12007400 | doi = 10.1016/S0092-8674(02)00718-3] Targets may include ribosomal and spliceosomal RNAs but the exact function of many snoRNAs, including U71, is unclear.

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