- Small nucleolar RNA SNORA51
Small nucleolar RNA SNORA51 (also known as ACA51) is a
non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of othersmall nuclear RNA s (snRNAs). This type of modifiying RNA is located in the nucleolus of theeukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.ACA51 was originally cloned fromHeLa cells cite journal | author = Kiss AM, Jady BE, Bertrand E, Kiss T | title = Human box H/ACA pseudouridylation guide RNA machinery | journal = Mol. Cell. Biol. | volume = 24 | issue = 13 | pages = 5797–807 | year = 2004 | pmid = 15199136 | doi = 10.1128/MCB.24.13.5797-5807.2004 | issn = ] and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein.References
External links
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* [http://www-snorna.biotoul.fr/plus.php?id=ACA51 snoRNAbase entry for ACA51]
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