Leucine operon leader

Leucine operon leader

The Leucine operon leader is an RNA element found upstream of the first gene in the Leucine biosynthetic operon.cite journal | author = Kolter R, Yanofsky C | title = Attenuation in amino acid biosynthetic operons | journal = Annu. Rev. Genet. | volume = 16 | issue = | pages = 113–34 | year = 1982 | pmid = 6186194 | doi = 10.1146/annurev.ge.16.120182.000553 | issn = ] The leader sequence can assume two different secondary structures known as the terminator and the anti-terminator structure. The leader also codes for very short peptide sequence that is rich in leucine amino acid. The terminator structure is recognised as a termination signal for RNA polymerase and the operon is not transcribed. This structure forms when the cell has an excess of leucine and ribosome movement over the leader transcript is not impeded. When there is a deficiency of the charged leucyl tRNA the ribosome translating the leader peptide stalls and the antiterminator structure can form. This allows RNA polymerase to transcribe the operon. At least 6 amino acid operons are known to be regulated by attenuation.

References

External links

*


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Non-coding RNA — A non coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. Less frequently used synonyms are non protein coding RNA (npcRNA), non messenger RNA (nmRNA) and functional RNA (fRNA). The term small RNA (sRNA) is… …   Wikipedia

  • List of genetics-related topics — This is a list of terms related to genetics. NOTOC # * 3 end * 5 end A * Acentric chromosome * Achondroplasia * Active site * Adam s Curse * Adaptation * Adenine * Adenosine * Adenovirus * Adenosine diphosphate (ADP) * Ala * Alagille syndrome *… …   Wikipedia

  • List of genetic engineering topics — NOTOC # 3 end 5 end A Acentric chromosome Achondroplasia Active site Adam s Curse Adaptation Adenine Adenosine Adenosine diphosphate Adenovirus ADP Ala Alagille syndrome Albino Alcoholism Alkylating agent Allele Allele frequency Alleles… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”