Hairy RNA localisation element (HLE)

The hairy localisation element (HLE) is an RNA element found in the 3' UTR of the hairy gene. HLE contains two stem-loops. HLE is essential for the mediation of apical localisation and the two stem-loop structures act to allow the recognition of hairy mRNA by the localisation machinery. [cite journal | last = Bullock | first = SL | coauthors = Zicha D, Ish-Horowicz D | year = 2003 | title = The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport | journal = EMBO J | volume = 22 | pages = 2484–2494 | pmid = 12743042 | doi = 10.1093/emboj/cdg230] HLE is found in "Drosophila" species.

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