C-sis internal ribosome entry site (IRES)

C-sis internal ribosome entry site (IRES)

The c-sis internal ribosome entry site (IRES) is a RNA element found in the 5' UTR of the PDGF beta chain gene. The internal ribosome entry site contains three modules that can individually mediate internal ribosome entry. However, the full length sequence is required for maximal IRES activity. It is thought that the three IRES elements are somehow responsive to cellular changes and act to regulate the level of translation. [cite journal | last = Sella | first = O | coauthors = Gerlitz G, Le SY, Elroy-Stein O | year = 1999 | title = Differentiation-induced internal translation of c-sis mRNA: analysis of the cis elements and their differentiation-linked binding to the hnRNP C protein | journal = Mol Cell Biol | volume = 19 | pages = 5429–5440 | pmid = 10409733]

References

External links

*


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Myc — V myc myelocytomatosis viral oncogene homolog (avian) Structure of the c Myc (red) in complex with Max (blue) and DNA (PDB 1nkp). Both proteins are binding the major groove of the DNA by forming a fork like structure …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”