- Bip internal ribosome entry site (IRES)
The BiP internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the
mRNA ofBiP protein and allows cap-independent translation. BiP protein expression has been found to be significantly enhanced by the heat shock response due tointernal ribosome entry site (IRES)-dependent translation. It is thought that this translational mechanism is essential for the survival of cells under stress [1] .References
* [1] cite journal | last = Kim | first = YK | coauthors = Jang SK | year = 2002 | title = Continuous heat shock enhances translational initiation directed by internal ribosomal entry site | journal = Biochem Biophys Res Commun | volume = 297 | pages = 224–231 | pmid = 12237106 | doi = 10.1016/S0006-291X(02)02154-X
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