Carbamoyl phosphate synthase II
- Carbamoyl phosphate synthase II
protein
Name=carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
caption=
width=
HGNCid=1424
Symbol=CAD
AltSymbols=
EntrezGene=790
OMIM=114010
RefSeq=NM_004341
UniProt=P27708
PDB=
ECnumber=
Chromosome=2
Arm=p
Band=21
LocusSupplementaryData=
Carbamoyl phosphate synthetase II is an enzyme that catalyzes the reactions that produce carbamoyl phosphate in the cytosol (as opposed to type I, which functions in the mitochondria).
In pyrimidine biosynthesis, it catalyzes the following reaction:
Gln + CO2 + 2 ATP + H2O → carbamoyl phosphate + Glu + 2 ADP + Pi
It is one of the three enzyme functions coded by the CAD gene. It is classified under EC number|6.3.5.5.
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