- Psychostimulant
A psychostimulant is a substance that enhances locomotor behavior. Examples of psychostimulants include
amphetamine ,methamphetamine ,cite web |url=http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/seven/000088218.htm |title=Dorlands Medical Dictionary:psychostimulant |format= |work= |accessdate=]cocaine ,methylphenidate , andarecoline , the most widely used psychostimulant. [cite journal |author=Gupta PC, Ray CS |title=Epidemiology of betel quid usage |journal=Ann. Acad. Med. Singap. |volume=33 |issue=4 Suppl |pages=31–6 |year=2004 |month=July |pmid=15389304 |doi= |url=http://www.annals.edu.sg/pdf200409/V33N4p31S.pdf]Nicotine andcaffeine are not considered psychostimulants because they do not enhance locomotor behavior in rodents.cite journal |author=Sulzer D, Sonders MS, Poulsen NW, Galli A |title=Mechanisms of neurotransmitter release by amphetamines: a review |journal=Prog. Neurobiol. |volume=75 |issue=6 |pages=406–33 |year=2005 |pmid=15955613 |doi=10.1016/j.pneurobio.2005.04.003]Psychostimulants are often potent modulators of
dopamine signaling, often affecting the activity ofmonoamine transporter s such as thedopamine transporter andvesicular monoamine transporter s. [cite journal |author=Riddle EL, Fleckenstein AE, Hanson GR |title=Role of monoamine transporters in mediating psychostimulant effects |journal=The AAPS journal |volume=7 |issue=4 |pages=E847–51 |year=2005 |pmid=16594636 |doi=10.1208/aapsj070481]References
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