- Defect Removal Efficiency, a metric used by Quality Control departments of businesses
- Dr. Dre, American record producer and rapper
- Mac Dre, deceased American rapper.
- Digital rectal examination
- Doctor of Religious Education
- Direct Recording Electronic voting machine
- Drug Recognition Expert
- Disc Read Error, a type of disk storage error, in computing
- Dre & Vidal
- Dry Rock Equivalent, useed in volcanology
- Andre 3000 formerly known as Dre but changed his name to separate himself from Dr. Dre.
- Andre Merritt, songwriter and member of Chris Brown's songwriting team, the Graffiti Artizts.
- Dre a 2010 album by American rapper, Soulja Boy Tell 'Em.
- Disability & Rehabilitation, a medical journal.
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