Paramethoxyethylamphetamine

Paramethoxyethylamphetamine

Drugbox
IUPAC_name = N-ethyl-1-(4-methoxyphenyl)propan-2-amine


width= 160
CAS_number= 14367-46-5
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PubChem= 85725
DrugBank=
C=12 | H=19 | O=1 | N=1
molecular_weight = 193.285 g/mol
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Para-methoxy-ethylamphetamine or PMEA is a stimulant drug related to PMA and ethylamphetamine.

PMEA reputedly produces similar effects to PMA, but is considerably less potent [ Bustamante D, Diaz-Veliz G, Paeile C, Zapata-Torres G, Cassels BK. Analgesic and behavioral effects of amphetamine enantiomers, p-methoxyamphetamine and n-alkyl-p-methoxyamphetamine derivatives. Pharmacology Biochemistry and Behavior. 2004 Oct;79(2):199-212. ] and seems to have slightly less tendency to produce severe hyperthermia, at least at low doses. At higher doses however the side effects and danger of death approach those of PMA itself, and PMEA should still be considered a potentially dangerous drug. Investigation of a drug-related death in Japan in 2005 showed PMEA to be present in the body and was thought to be responsible for the death. [Zaitsu K, Katagi M, Kamata T, Kamata H, Shima N, Tsuchihashi H, Hayashi T, Kuroki H, Matoba R. Determination of a newly encountered designer drug "p-methoxyethylamphetamine" and its metabolites in human urine and blood. "Forensic Science International". 2008 May 2;177(1):77-84. PMID 18155375]

CAS number: 93963-24-7 (hydrochloride)

References


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