Trypsinogen

Trypsinogen

Trypsinogen (EC 3.4.23.18/20/21/23/24/26) is the precursor form of the pancreatic enzyme trypsin or a zymogen. It is found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen. It is activated by enteropeptidase, which is found in the intestinal mucosa, to form trypsin. Once activated, the trypsin can activate more trypsinogen into trypsin.Trypsin cleaves peptide bond on carboxyl side of basic aminoacids.

Serum trypsinogen is measured using a blood test. High levels are seen in acute pancreatitis, and cystic fibrosis.

Functions

* Protein digestion.

External links

*


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  • Trypsinogen — [Trypsin + Gen.] (Physiol.) ist die abgesonderte (sezerniert) Vorstufe (Proenzym) des Pankreas Enzyms Trypsin. Es wird genauso wie Chymotrypsinogen, Proelastase und andere Enzyme in inaktiver Form sezerniert. Bedeutung Das inaktive Proenzym… …   Deutsch Wikipedia

  • Trypsinogen — Tryp*sin o*gen, n. [Trypsin + gen.] (Physiol.) The antecedent of trypsin, a substance which is contained in the cells of the pancreas and gives rise to the trypsin. [1913 Webster] …   The Collaborative International Dictionary of English

  • Trypsinogen — ⇒ Trypsin …   Deutsch wörterbuch der biologie

  • trypsinogen — [trip sin′ə jən] n. [ TRYPSIN + O + GEN] the inactive precursor of trypsin, secreted by the pancreas …   English World dictionary

  • trypsinogen — tripsinogenas statusas T sritis chemija apibrėžtis Neaktyvi tripsino forma. atitikmenys: angl. trypsinogen rus. трипсиноген …   Chemijos terminų aiškinamasis žodynas

  • trypsinogen — noun Etymology: International Scientific Vocabulary Date: circa 1890 the inactive substance released by the pancreas into the duodenum to form trypsin …   New Collegiate Dictionary

  • trypsinogen — /trip sin euh jeuhn, jen /, n. Biochem. a precursor of trypsin that is secreted by the pancreas and is activated to trypsin in the small intestine. [1885 90; TRYPSIN + O + GEN] * * * …   Universalium

  • trypsinogen — noun An inactive precursor of trypsin …   Wiktionary

  • Trypsinogen — Tryp|si|no|gen [↑ gen], das; s, e: ↑ Trypsin …   Universal-Lexikon

  • trypsinogen — tryp·sin·o·gen trip sin ə jən n the inactive substance released by the pancreas into the duodenum to form trypsin * * * n. see trypsin * * * tryp·sin·o·gen (trip sinґo jən) the inactive proenzyme of trypsin secreted by the pancreas,… …   Medical dictionary

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