FXYD6

protein
Name=FXYD domain containing ion transport regulator 6
caption=


width=
HGNCid=4030
Symbol=FXYD6
AltSymbols=
EntrezGene=53826
OMIM=606683
RefSeq=NM_022003
UniProt=Q9H0Q3
PDB=
ECnumber=
Chromosome=11
Arm=q
Band=23.3
LocusSupplementaryData=

FXYD6 (pronounced fix-id six), or FXYD domain-containing ion transport regulator 6, is a gene which is located at the 11q23.3 (chromosome 11 locus 23.3). The FXYD6 protein contains 95 amino acids, and can be found in all human tissues except blood.

This gene belongs to the FXYD family of ion transport regulators [ [http://www.sanger.ac.uk/cgi-bin/Pfam/getacc?PF02038 ATP1G1/PLM/MAT8 family in PFAM] ]

Pathology

According to recent research, its pathologies may cause a predisposition to schizophrenia. [ [http://www.schizophreniaforum.org/new/detail.asp?id=1326 Getting Crowded on Chromosome 11q22—Make Way for Phosphohippolin] ] [cite journal |author=Choudhury K, McQuillin A, Puri V et al |title=A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia |journal=Am. J. Hum. Genet. |volume=80 |issue=4 |pages=664–72 |year=2007 |pmid=17357072 |doi=10.1086/513475]

References

External links

* [http://www.genecards.org/cgi-bin/carddisp.pl?gene=FXYD6 GeneCards page about the gene]