- Mesomark assay
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The Mesomark Assay is an in vitro test to monitor and possibly diagnose Pleural Mesothelioma and Peritoneal Mesothelioma.[1]
Developed by Fujirebio Diagnostics and approved in late January 2007 by the U.S. Food and Drug Administration (FDA), it works by measuring levels of soluble mesothelin-related proteins (SMRPs) released by diseased mesothelioma cells. The SMRP levels correlate directly with tumor volume thus permitting less invasive monitoring and improved assessment of treatment response.
In the future, the test may be used as an early detection measure as evidenced by recently sponsored tests by the Early Detection Research Network of the National Cancer Institute [1].
References
- ^ Beyer, HL, Geschwindt RD et al. (April 2007). "MESOMARK: a potential test for malignant pleural mesothelioma". Clinical Chemistry 53 (4): 666–672. doi:10.1373/clinchem.2006.079327. PMID 17289801.
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