Guanosine nucleotide dissociation inhibitors
- Guanosine nucleotide dissociation inhibitors
The Guanosine nucleotide dissociation inhibitors (GDIs), bind to the GDP-bound form of Rho and Rab small GTPases and not only prevent exchange (maintaining the small GTPase in an off-state), but also prevent the small GTPase from localizing at the membrane, which is their place of action.
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*MeshName|Guanine+Nucleotide+Dissociation+Inhibitors
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