Mad1

Mad1

MAD1 mitotic arrest deficient-like 1 (yeast), also known as MAD1L1, is a human gene.cite web | title = Entrez Gene: MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8379| accessdate = ]

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summary_text = MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.cite web | title = Entrez Gene: MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8379| accessdate = ]

ee also

* MAD2
* Hyperphosphorylation

References

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