- Primordial sandwich
The concept of the primordial sandwich was proposed by the
chemist Günter Wächtershäuser to describe the possible origins of the firstcell membrane s, and, therefore, the first cell.According to the two main models of
abiogenesis , RNA world and iron-sulfur world, prebiotic [From the roots pre (meaning before) and biotic (referring to life), the word prebiotic can refer to the time before life appeared on the earth or any other planet with the capacity to harbor it.] processes existed "before" the development of the cell membrane. The difficulty with this idea, however, is that it is almost impossible to create a complex molecule such as RNA (or even its molecular precursor, pre-RNA) directly from simple organic molecules dissolved in a global ocean (Joyce, 1991), because without some mechanism to concentrate these organic molecules, they would be too dilute to generate the necessarychemical reaction s to transform them from simple organic molecules into genuine prebiotic molecules.To address this problem, Wächtershäuser proposed that concentration might occur by concentration upon ("
adsorption to") the surfaces of minerals. With the accumulation of enoughamphipathic molecules (such asphospholipid s), abilayer will self-organize, and any molecules caught inside will become the contents of aliposome , and would be concentrated enough to allow chemical reactions to transform organic molecules into prebiotic molecules.Although developed for his own iron-sulfur world model, the idea of the "primordial sandwich" has also been adopted by some adherents of the
RNA world model.ee also
*
Primordial sea Notes
Additional information
* [http://www.earth.cardiff.ac.uk/admissions/phd/PhDtopicDetails/minerals-life.html Minerals and the Origin of Life]
* [http://astrobiology.gsfc.nasa.gov/deamer_2002.pdf Astrobiology, Volume 2, Number 4, "The First Cell Membranes"]
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