Cellulose acetate phthalate
- Cellulose acetate phthalate
Cellulose acetate phthalate is a commonly used polymer phthalate in the formulation of pharmaceuticals, such as the enteric coating of tablets or capules. It is a cellulose polymer with substituted phthalates at the hydroxyl positions. Its main use in pharmaceutics is with enteric formulations. Cellulose acetate phthalate is also commonly plasticized with diethyl phthalate, a hydrophobic compound, or Triethyl citrate, a hydrophilic compound.
According to a 1944 study by Hodge, there was no histological change on rats fed CAP for a year.
References
Pharmaceutical Development and Technology, 6(4), 607-6149 (2001)
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