GAKIC

GAKIC is a brand name for a widely available nutritional supplement which, among other ingredients, contains a formulation of the glycine and L-arginine salt of alpha-ketoisocaproic acid calcium. GAKIC is a registered trademark. Clinical studies in humans demonstrate that oral consumption of this formulation enhances muscle performance and recovery from fatigue by sustaining muscle force and work output during intense anaerobic exercise. Clinical investigations demonstrating the effects of of this formulation include the use of isokinetic dynamometer telemetry [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11128858&query_hl=1&itool=pubmed_docsum] [http://iospress.metapress.com/(fd1zgw451qkeml31jzcufc55)/app/home/contribution.asp?referrer=parent&backto=issue,5,7;journal,26,31;linkingpublicationresults,1:103163,1] [http://www.acsm-msse.org/pt/re/msse/abstract.00005768-199805001-00397.htm;jsessionid=FrsJrB80jnRYTCpTjBQdkQxTRL1L2wkmfr41PyWc246tmdBJXMLf!2118075020!-949856145!8091!-1] , and Wingate sprint cycle ergometry [http://www.ms-se.com/pt/re/msse/abstract.00005768-200404000-00005.htm;jsessionid=FrtJ2HY9d0njrqlc24Vm4pTvyRm0qhxpVyCSSBGn8kv9TXx7gyd5!1134402189!-949856144!8091!-1] . The patent [http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN%2F6100287] assignee for GAKIC is University of Florida.

References

*cite journal | author=Stevens, B.R., Godfrey, M.D., Kaminski, T.W., and Braith, R.W. |url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11128858&query_hl=1&itool=pubmed_docsum| title=High intensity dynamic human muscle performance enhanced by a metabolic intervention | journal=Med. Sci. Sports Exerc.| volume=32 |year=2000 | pages=2102–2108| doi=10.1097/00005768-200012000-00021

*cite journal | author=Kaminski, T.W., Godfrey, M.D., Braith, R.W., and Stevens, B.R. |url=http://iospress.metapress.com/(fd1zgw451qkeml31jzcufc55)/app/home/contribution.asp?referrer=parent&backto=issue,5,7;journal,26,31;linkingpublicationresults,1:103163,1| title=Measurement of acute dynamic anaerobic muscle fatigue using a novel fatigue resistance index| journal=Isokinetics Exerc. Sci.| volume=8 |year=2000 | pages=1–7

*cite journal | author=Godfrey, M.D., Braith, R.W., Kaminski, T.W., and Stevens, B.R. |url=http://www.acsm-msse.org/pt/re/msse/abstract.00005768-199805001-00397.htm;jsessionid=FrsJrB80jnRYTCpTjBQdkQxTRL1L2wkmfr41PyWc246tmdBJXMLf!2118075020!-949856145!8091!-1| title=Quantification of exhaustive muscle function following isocaloric metabolic interventions | journal=Med. Sci. Sports Exerc.| volume=30 | issue=5| year=1998 | pages=S70| doi=10.1097/00005768-199805001-00397

*cite journal | author=Buford, B.N., and A.J. Koch. |url=http://www.ms-se.com/pt/re/msse/abstract.00005768-200404000-00005.htm;jsessionid=FrtJ2HY9d0njrqlc24Vm4pTvyRm0qhxpVyCSSBGn8kv9TXx7gyd5!1134402189!-949856144!8091!-1| title=Glycine-arginine-alpha ketoisocaproic acid improves performance of repeated cycling sprints | journal=Med. Sci. Sports Exerc.| volume=34 | issue=5 |year=2004 | pages=583–587| doi=10.1249/01.MSS.0000122075.14060.C4

* " [http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN%2F6100287 US Patent 6,100,287] "